Score Overview
Explore the 2021 public Archive ranking →
Where Spyre Therapeutics Inc. has ranked, year by year
Not enough ranking history to display a chart
This chart needs at least two years of available HDB Score rankings on 10 years of fundamentals. SYRE does not have enough ranked years in the public Archive through 2021.
More recent Archive years are available with Membership. Coverage varies by company and measure.
Net Income x Stock Price
Historical Returns
| Period | Price | Return |
|---|---|---|
Last Price2026-10-23 | $ 90.33 | — |
1 Year2025-10-23 | $ 22.37 | 303.80% |
5 Years2021-10-22 | $ 182.50 | -50.50% |
10 Years2016-10-21 | $ 156.75 | -42.37% |
All Time2016-04-07 | $ 244.25 | -63.02% |
| Period | Last Price2026-10-23 | 1 Year2025-10-23 | 5 Years2021-10-22 | 10 Years2016-10-21 | All Time2016-04-07 |
|---|---|---|---|---|---|
| Price | $ 90.33 | $ 22.37 | $ 182.50 | $ 156.75 | $ 244.25 |
| Return | — | 303.80% | -50.50% | -42.37% | -63.02% |
Prices are split & dividend adjusted. All values are reported in USD.
Fundamental Data
Reported in USD
| Year | |||
|---|---|---|---|
| TTM | $ 90M | -$ 178M | $ 1.14B |
| 2025 | $ 0.00 | -$ 155M | $ 756M |
| 2024 | $ 886K | -$ 208M | $ 603M |
| 2023 | $ 886K | -$ 338M | $ 339M |
| 2022 | $ 2M | -$ 83M | $ 55M |
| 2021 | $ 18M | -$ 65M | $ 93M |
| 2020 | $ 0.00 | -$ 80M | $ 146M |
| 2019 | $ 0.00 | -$ 78M | $ 71M |
| 2018 | $ 3M | -$ 44M | $ 74M |
| 2017 | $ 5M | -$ 27M | $ 50M |
| IPO2016 | $ 4M | -$ 21M | $ 63M |
Spyre Therapeutics Inc. fundamental performance
Between 2020 and 2025, revenue held from $ 0.00 to $ 0.00 and net income went from -$ 80M to -$ 155M. Revenue increased in 1 of those 5 years; net income in 2.
Across Spyre Therapeutics Inc.'s full reported history, from 2016 to 2025, revenue declined from $ 4M to $ 0.00 and net income went from -$ 21M to -$ 155M. Revenue increased in 30% of the years measured; net income in 30%.
Spyre Therapeutics Inc. currently holds a 5-year HDB Score of 3.2 out of 10. How the HDB Score is calculated.
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The public Archive runs through 2021. Membership adds recent and current rankings.
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