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Karyopharm Therapeutics Inc

KPTI
Rev 952xtop 1%10Y
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Karyopharm Therapeutics develops and commercializes drugs targeting nuclear export for cancer treatment, focusing on small molecule inhibitors like XPOVIO and Selinexor. Its key applications include multiple myeloma and various solid tumors.

โš•๏ธ Healthcare NASDAQ Listed 2013 $ USD
$1,000 invested 10 years ago โ†’$4today

Score Overview

1 Year
Score
Net Growth-14.64%
Net TrendShrank
Net Income Consistencyโ€”
Rev Growth0.38%
Rev TrendGrew
Revenue Consistencyโ€”
5 Years
Score3.0
Net Growth-81.11%
Net Trend40%
Net Income Consistencyโ€”
Rev Growth-30.12%
Rev Trend40%
Revenue Consistencyโ€”
10 Years
Score
Net Growth-105.10%
Net Trend40%
Net Income Consistency
Rev Growth952x
Rev Trend70%
Revenue Consistency
All Time
Score
Net Growth-4x
Net Trend38%
Net Income Consistency
Rev Growth378x
Rev Trend62%
Revenue Consistency

Explore the 2021 public Archive ranking โ†’

Where Karyopharm Therapeutics Inc has ranked, year by year

Measure
Fundamentals Window

Not enough ranking history to display a chart

This chart needs at least two years of available HDB Score rankings on 10 years of fundamentals. KPTI does not have enough ranked years in the public Archive through 2021.

More recent Archive years are available with Membership. Coverage varies by company and measure.

Net Income x Stock Price

Historical Returns

Historical Returns
PeriodPriceReturn
Last Price2026-10-22
$ 0.55โ€”
1 Year2025-10-22
$ 6.14-91.11%
5 Years2021-10-22
$ 79.05-99.31%
10 Years2016-10-21
$ 128.85-99.58%
All Time2013-11-06
$ 240.75-99.77%

Prices are split & dividend adjusted. All values are reported in USD.

Fundamental Data

Reported in USD

Year
TTM$ 146M-$ 224M$ 65M
2025$ 146M-$ 196M$ 63M
2024$ 145M-$ 76M$ 108M
2023$ 146M-$ 143M$ 191M
2022$ 157M-$ 165M$ 277M
2021$ 209M-$ 124M$ 228M
2020$ 108M-$ 196M$ 273M
2019$ 40M-$ 199M$ 263M
2018$ 30M-$ 178M$ 328M
2017$ 1M-$ 128M$ 146M
2016$ 154K-$ 109M$ 129M
2015$ 250K-$ 118M$ 175M
2014$ 229K-$ 75M$ 205M
IPO2013$ 387K-$ 33M$ 155M
KPTI - Karyopharm Therapeutics Inc logo

Karyopharm Therapeutics Inc fundamental performance

Between 2020 and 2025, revenue grew from $ 108M to $ 146M and net income went from -$ 196M to -$ 196M. Revenue increased in 2 of those 5 years; net income in 2.

Across Karyopharm Therapeutics Inc's full reported history, from 2013 to 2025, revenue grew from $ 387K to $ 146M and net income went from -$ 33M to -$ 196M. Revenue increased in 62% of the years measured; net income in 38%.

Karyopharm Therapeutics Inc currently holds a 5-year HDB Score of 3.0 out of 10. How the HDB Score is calculated.

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