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Spero Therapeutics Inc

SPRO

Spero Therapeutics develops novel treatments for multi-drug resistant bacterial infections and rare diseases, focusing on oral antibiotics like Tebipenem HBr for complicated urinary tract infections, in partnership with various pharmaceutical firms.

โš•๏ธ Healthcare NASDAQ Listed 2017 $ USD
$1,000 invested 5 years ago โ†’$66today

Score Overview

1 Year
Score
Net Growth97.56%
Net TrendGrew
Net Income Consistencyโ€”
Rev Growth-27.94%
Rev TrendShrank
Revenue Consistencyโ€”
5 Years
Score7.2
Net Growth118.87%
Net Trend80%
Net Income Consistencyโ€”
Rev Growth13x
Rev Trend60%
Revenue Consistencyโ€”
All Time
Score
Net Growth136.74%
Net Trend56%
Net Income Consistency
Rev Growth21x
Rev Trend67%
Revenue Consistency

Explore the 2021 public Archive ranking โ†’

Where Spero Therapeutics Inc has ranked, year by year

Measure
Fundamentals Window

Not enough ranking history to display a chart

This chart needs at least two years of available HDB Score rankings on 10 years of fundamentals. SPRO does not have enough ranked years in the public Archive through 2021.

More recent Archive years are available with Membership. Coverage varies by company and measure.

Net Income x Stock Price

Historical Returns

Historical Returns
PeriodPriceReturn
Last Price2026-10-23
$ 1.11โ€”
1 Year2025-10-23
$ 2.20-49.55%
5 Years2021-10-22
$ 16.86-93.42%
All Time2017-11-02
$ 11.50-90.35%

Prices are split & dividend adjusted. All values are reported in USD.

Fundamental Data

Reported in USD

Year
TTM$ 42M$ 16M$ 50M
2025$ 59M$ 8M$ 40M
2024$ 47M-$ 68M$ 52M
2023$ 103M$ 22M$ 76M
2022$ 48M-$ 46M$ 109M
2021$ 3M-$ 89M$ 146M
2020$ 9M-$ 77M$ 126M
2019$ 4M-$ 60M$ 82M
2018$ 3M-$ 41M$ 115M
IPO2017$ 1M-$ 46M$ 87M
SPRO - Spero Therapeutics Inc logo

Spero Therapeutics Inc fundamental performance

Between 2020 and 2025, revenue grew from $ 9M to $ 59M and net income went from -$ 77M to $ 8M. Revenue increased in 3 of those 5 years; net income in 4.

Across Spero Therapeutics Inc's full reported history, from 2017 to 2025, revenue grew from $ 1M to $ 59M and net income went from -$ 46M to $ 8M. Revenue increased in 67% of the years measured; net income in 56%.

Spero Therapeutics Inc currently holds a 5-year HDB Score of 7.2 out of 10. How the HDB Score is calculated.

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